Endocrine Abstracts

Introduction: Hirsutism affects 5–8% of the whole female population. In most patients, hirsutism is associated with hyperandrogenemia and the most common cause of androgen excess is polycystic ovary syndrome; however, the clinical presentation of non-classical congenital adrenal hyperplasia(NCAH) in females is often indistinguishable from other hyperandrogenic disorders because of common clinical signs with hirsutism and poly cystic ovary syndrome(PCOS).<p class="abst...

Introduction: The pathogenesis of idiopathic hirsutism (IH) is not clear. On the other hand, human skin possesses all the enzymes necessary for androgen synthesis and catabolism indicating that it is an independent peripheral endocrine organ. Thus, in the present study we aimed to investigate the mRNA expression of aromatase enzyme and the other enzymes having functional roles in the steroidogenic pathway, in freshly obtained skin tissue from subumblical skin and the arm of wo...